Primary Congenital Glaucoma: A Comprehensive Review of Epidemiology, Pathogenesis, Diagnosis, and Surgical Management.

Abstract

Primary congenital glaucoma (PCG) is a non-syndromic, potentially blinding ocular disease manifesting in early childhood. It is characterized by elevated intraocular pressure (IOP) and progressive expansion of the globe (buphthalmos) due to isolated goniodysgenesis. By definition, PCG occurs in the absence of other ocular or systemic anomalies and is not secondary to previous ocular surgery. Clinical classification is traditionally based on the age of onset:^1,2